"The big changes are the formal integration of coronary artery calcium scoring, the formal integration of polygenic risk scoring, the explicit recommendation for Lp(a) screening, and a more formal involvement of apolipoprotein B as a risk measure."
"These guidelines also call out special populations that might benefit from additional care: individuals with obesity and diabetes, individuals with chronic kidney disease, individuals with hypertensive disorders of pregnancy and other reproductive risk factors."
"This is an attempt to move toward more holistic care based on an understanding of the risk that most people encounter, and then to address, in a more personalized fashion, groups that are at additional high risk."
U.S. medical organizations have updated heart disease prevention guidelines, emphasizing lifelong strategies beginning in childhood. Key changes include the incorporation of coronary artery calcium scoring, polygenic risk scoring, and Lp(a) screening. The guidelines also identify special populations needing additional care, such as those with obesity, diabetes, chronic kidney disease, and specific genetic risks. This approach aims for personalized care, addressing the unique risks faced by various high-risk groups, including South Asian and Filipino individuals, to reduce heart disease mortality.
Read at Harvard Gazette
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