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Cancer
fromNature
2 days ago

Why some cancer-fighting immune cells lose their strength inside tumours

Mitochondrial health in dendritic cells is crucial for effective immune response against tumors, potentially enhancing cancer immunotherapy effectiveness.
#cancer
Cancer
fromBusiness Insider
2 weeks ago

Stop ignoring subtle signs of cancer. A doctor explains when to get medical help.

Early cancer symptoms are often subtle and easily missed, including unexplained fatigue, persistent pain, and digestive changes; persistent symptoms lasting over a week warrant medical evaluation.
Medicine
fromenglish.elpais.com
1 month ago

A living drug manages to eliminate tumors in mice with pancreatic, ovarian and kidney cancer

An ultrasensitive CAR-T cell therapy successfully eliminated solid tumors in laboratory mice by targeting the CD70 protein at previously undetectable levels.
Cancer
fromNature
1 month ago

Cancer blood tests are everywhere. Do they really work?

Multi-cancer early detection blood tests show promise but lack regulatory approval and rigorous trial evidence, with initial results indicating limited effectiveness in improving cancer outcomes.
Cancer
fromBusiness Insider
1 month ago

A new report reveals that a third of colon cancer cases now occur in the rectum. Take these steps to protect yourself at any age.

Rectal cancer cases are rising dramatically in people under 50, doubling from 1998 to 2022, suggesting an environmental or behavioral trigger rather than lifestyle factors alone.
#breast-cancer
fromBusiness Insider
2 months ago
Medicine

An OB-GYN pushed for a preventive double-mastectomy in her 40s. A week later, she learned she had stage 1 breast cancer.

fromBusiness Insider
2 months ago
Medicine

An OB-GYN pushed for a preventive double-mastectomy in her 40s. A week later, she learned she had stage 1 breast cancer.

Science
fromwww.dw.com
1 month ago

'Remarkable' new cat cancer genome could benefit humans

Cats and humans develop similar cancers due to shared tumor-causing genetic mutations, suggesting cats could improve cancer research and treatments for both species.
Cancer
fromFuturism
1 month ago

Bacteria Engineered to Eat Tumors From the Inside

Researchers engineered Clostridium sporogenes bacteria to consume tumor cells from inside, offering a potential alternative to traditional cancer treatments.
Medicine
fromMail Online
1 month ago

Scientists say the secret to curing cancer could live in your pet CAT

Genetic alterations in common cat cancers mirror those in humans, revealing shared mechanisms and opportunities for cross-species targeted therapies.
Cancer
fromBusiness Insider
1 month ago

I almost brushed off sharp stomach pain - it turned out to be stage 3 colon cancer

Mark Seguin was diagnosed with colon cancer at age 35 after experiencing recurring severe stomach pain caused by a tumor blocking his colon, though no obvious warning signs preceded the diagnosis.
OMG science
fromHarvard Gazette
2 months ago

Why did that cancer cell become drug-resistant? - Harvard Gazette

TimeVault records and stores cellular gene-expression history inside living cells, enabling retrieval of past gene-activity information to study differentiation, stress responses, adaptation, and drug resistance.
fromwww.nature.com
1 month ago

Author Correction: The genomic landscape of response to EGFR blockade in colorectal cancer

In Extended Data Fig. 8 of this article, a micrograph shown in the left column (panel AZD) was inadvertently duplicated during figure preparation. The intended image was meant to show phospho-ERK (P-ERK) levels in a MAP2K1-mutant patient-derived xenograft (PDX) exposed to the MEK inhibitor AZD6244 (AZD). However, this image was accidentally overlaid with a micrograph from Extended Data Fig. 10 (left column, panel PAN), which displays P-ERK levels in an EGFR-mutant PDX exposed to panitumumab (PAN).
fromwww.theguardian.com
1 month ago

What is colorectal cancer and is it preventable?

Actor James Van Der Beek died on 11 February, aged 48; he had been diagnosed in 2023 with colorectal cancer. According to the World Health Organization, colorectal cancer is the third most common cancer and the second leading cause of cancer-related deaths worldwide. While rates are declining overall, cases among younger people are rising. This is a curable cancer if diagnosed early, says Dr Deirdre Cohen, director of the gastrointestinal oncology program for the Mount Sinai health system and an associate professor of medicine. It's important to bring any symptoms to the attention of your physician.
Public health
fromNature
2 months ago

Why cancer can come back years later - and how to stop it

When Lisa Dutton was declared free of breast cancer in 2017, she took a moment to celebrate with family and friends, even though she knew her cancer journey might not be over. As many as one-third of people whose breast tumours are cleared see the disease come back, sometimes decades later. Many other cancers are known to recur in the years following an initial treatment, some at much higher rates.
Medicine
#bowel-cancer
Science
fromNature
2 months ago

Cancer might evade immune defences by stealing mitochondria

Cancer cells acquire mitochondria from immune cells to weaken those immune cells and activate type I interferon signaling that promotes lymph-node invasion.
Medicine
fromwww.theguardian.com
2 months ago

Simple blood test can predict which breast cancer treatment will work best, study finds

A blood test measuring circulating tumour DNA predicts breast cancer treatment response before or within four weeks, enabling alternative therapies and avoiding ineffective drugs.
fromwww.scientificamerican.com
1 month ago

Lung cancer hijacks the brain to trick the immune system

For years, scientists have viewed cancer as a localized glitch in which cells refuse to stop dividing. But a new study suggests that, in certain organs, tumors actively communicate with the brain to trick it into protecting them. Scientists have long known that nerves grow into some tumors and that tumors containing lots of nerves usually lead to a worse prognosis.
Science
fromwww.scientificamerican.com
2 months ago

Cancer Survival Rates Are the Highest They've Been since the 1970s

On Tuesday the American Cancer Society (ACS) released its annual report on cancer statistics in the U.S., and it offered a rare bit of good news: the proportion of people who were alive at least five years after a cancer diagnosis hit a record high. The report found that, among all cancer patients diagnosed between 2015 and 2021 in the U.S., the survival rate at the five-year mark relative to those who didn't have cancer was 70 percent.
Public health
#pancreatic-cancer
Science
fromScienceDaily
2 months ago

Vitamin A may be helping cancer hide from the immune system

Retinoic acid signaling in cancer cells and dendritic cells suppresses anti-tumor immunity, and blocking this pathway restores vaccine effectiveness.
fromenglish.elpais.com
2 months ago

A vaccine to prevent colon cancer shows promising results

Eduardo Vilar-Sanchez has spent more than 10 years pursuing a goal that seemed very distant, but which he now sees as a little closer: to develop a preventive vaccine against cancer. The physician and researcher is leading a study that presented the first promising results of a colon cancer vaccine in a small group of patients suffering from a rare disease that makes them 17 times more likely to develop colon cancer than the general population.
Medicine
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