#disease-susceptibility

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fromFast Company
23 hours ago

AI is coming for superbugs

Antibiotics are essential for modern medicine, but bacteria are evolving and developing resistance, turning routine infections into life-threatening conditions. A global analysis estimates that antibiotic-resistant infections could cause over 39 million deaths by 2050.
Medicine
#genetics
Health
fromThe Washington Post
2 days ago

One way to live longer: Win the genetic lottery

Genetic factors account for about 50% of human lifespan, significantly higher than the previously estimated 20%.
Health
fromThe Washington Post
2 days ago

One way to live longer: Win the genetic lottery

Genetic factors account for about 50% of human lifespan, significantly higher than the previously estimated 20%.
Exercise
fromScienceDaily
1 week ago

Just a few minutes of effort could lower your risk of 8 major diseases

Just a few minutes of vigorous activity daily can significantly reduce the risk of major diseases like heart disease and dementia.
#alzheimers-disease
fromInsideHook
2 months ago
Medicine

Scientists Explore Cancer's Connection to Alzheimer's Disease

Certain cancers produce proteins that cross the blood–brain barrier and recruit immune cells, reducing amyloid plaque accumulation and potentially lowering Alzheimer's disease risk.
fromNature
2 months ago
Medicine

Cancer might protect against Alzheimer's - this protein helps explain why

A protein secreted by cancer cells infiltrates the brain and breaks apart misfolded protein clumps linked to Alzheimer's, suggesting a potential therapeutic pathway.
Medicine
fromSocial Media Explorer
2 days ago

The Silent Two-Decade Build-Up of Alzheimer's - Social Media Explorer

Changes in the brain associated with Alzheimer's can begin years before symptoms appear, yet assessments often occur only after noticeable cognitive decline.
#antibiotic-resistance
OMG science
fromwww.npr.org
1 week ago

Here's some new dirt on a source of antibiotic resistance

Bacteria are increasingly resistant to antibiotics, with drought contributing to this rise in resistance and impacting human health.
OMG science
fromwww.npr.org
1 week ago

Here's some new dirt on a source of antibiotic resistance

Bacteria are increasingly resistant to antibiotics, with drought contributing to this rise in resistance and impacting human health.
Health
fromScienceDaily
1 week ago

This dangerous combo in your body could raise death risk by 83%

Sarcopenic obesity, characterized by excess belly fat and low muscle mass, significantly increases mortality risk by 83%. Early detection is crucial.
Medicine
fromwww.bbc.com
1 week ago

Our skin is falling off and no-one can tell us why

Topical steroid withdrawal (TSW) is a serious condition affecting many eczema patients, leading to severe skin reactions and inadequate medical recognition.
Coronavirus
fromMail Online
2 weeks ago

Climate change is fuelling deadly disease outbreaks, study warns

Climate change-driven extreme weather events directly cause disease outbreaks, with 60% of Peru's 2023 dengue cases linked to cyclone-induced rainfall and warm temperatures.
fromThe Atlantic
3 weeks ago

I Remember a World Without Vaccines

I am open-minded; I believe in integrative practices, and I agree that the medical establishment can be arrogant and unduly influenced by the pharmaceutical industry, which now funds so much of medical research. But I fully understand Scherer's frustration with his interminable discussions with Kennedy about scientific articles.
Coronavirus
fromNebraska Examiner
3 weeks ago

3 states and New York City join global disease response network * Nebraska Examiner

GOARN, which includes more than 310 national public health agencies, United Nations agencies, academic institutions, and nongovernmental groups, helps identify and manage infectious disease outbreaks worldwide. Since it was established in 2000, GOARN says it has helped manage more than 175 global health emergencies across 114 countries.
Public health
Medicine
fromenglish.elpais.com
2 weeks ago

Why some people get hooked and others don't: genetics, childhood and brain circuits explain addiction

Addiction is a mental disorder requiring professional treatment, not a matter of willpower or personal choice, yet society continues to stigmatize it as a moral failing.
Coronavirus
fromCbsnews
3 weeks ago

More serious mpox strain detected in NYC for first time

New York City confirmed its first clade I mpox case in a traveler from Europe; clade I causes more severe disease than clade II, and vaccination is recommended for at-risk populations.
Public health
fromwww.theguardian.com
3 weeks ago

Trump policies set to increase rates of lung disease and death, study finds

Trump administration policies across healthcare, environment, workplace, and vaccines are projected to significantly increase lung disease rates and premature deaths among Americans.
Mental health
fromPsychology Today
1 month ago

A Genetic Map Redrawing the Borders of Mental Illness

Five broad genetic families underlie 14 psychiatric disorders, suggesting diagnostic categories reflect shared biological landscapes rather than distinct diseases.
Cancer
fromwww.theguardian.com
1 month ago

Quarter of healthy years lost to breast cancer are due to lifestyle factors, research finds

Over 25% of healthy years lost to breast cancer result from lifestyle factors including red meat consumption and smoking, with projections showing global cases rising from 2.3 million to 3.5 million by 2050.
Public health
fromNature
3 weeks ago

Capturing dynamic phage-pathogen coevolution by clinical surveillance - Nature

Phage-inducible chromosomal island-like elements (PLEs) in Vibrio cholerae provide defense against ICP1 phage predation, influencing pandemic strain evolution and disease severity through dynamic phage-bacteria interactions.
Coronavirus
fromArs Technica
3 weeks ago

We study pandemics, and the resurgence of measles is a grim sign of what's coming

Measles outbreaks impose substantial economic costs through containment, medical expenses, and productivity losses, while declining vaccination coverage threatens control of multiple infectious diseases.
Alternative medicine
fromwww.scientificamerican.com
1 month ago

Help yourself to stronger immunity

The immune system can be enhanced through science-backed interventions including specific supplements, vaccines, and exercise, with omega-3 fatty acids and curcumin showing evidence of effectiveness while vitamin D proves less beneficial than previously claimed.
#tuberculosis-outbreak
Coronavirus
fromwww.mercurynews.com
4 weeks ago

Why the Bay Area has been a tuberculosis hotspot for more than a century

The Bay Area experiences tuberculosis rates three times the national average due to its ports and immigration history, with over 200 high school students recently infected in San Francisco.
Public health
fromThe Mercury News
4 weeks ago

Why the Bay Area has been a tuberculosis hotspot for more than a century

The Bay Area has tuberculosis rates three times the national average due to its ports and immigration history, with over 90% of active cases occurring among immigrants from countries with limited vaccine access.
Medicine
fromThe New Yorker
1 month ago

Could a Cancer Treatment Cure Autoimmune Diseases?

CAR-T cell therapy, originally developed for cancer treatment, now shows promise for treating previously incurable autoimmune diseases like lupus and multiple sclerosis.
Medicine
fromPsychology Today
1 month ago

The Process of Being Diagnosed With a Rare Condition

Sphincter of Oddi dysfunction is a rare condition affecting digestive juice flow that causes severe abdominal pain and is often overlooked in medical diagnosis despite being treatable.
Science
fromwww.bbc.com
1 month ago

Single vaccine could protect against all coughs, colds and flus, researchers say

A single nasal spray vaccine induces lung macrophage readiness, offering broad protection against viruses, multiple bacteria, and potentially allergies for months.
#air-pollution
fromwww.npr.org
1 month ago

Scientists find a new clue to help them identify a healthy gut microbiome

There are some communities that are very unhealthy where the diversity is higher. Low diversity is not a universal marker. We found something that at first seemed surprising. That a healthy microbiome has lots of competition. These bugs are all going after the same food. In an unhealthy gut, on the other hand, you see tight cooperation - microorganisms are helping each other out.
Medicine
Cancer
fromenglish.elpais.com
1 month ago

Douglas Hanahan, biologist: We don't necessarily need a cure, what we really need is cancer without disease'

Cancer cells acquire hallmarks: uncontrolled proliferation, evasion of growth barriers, resistance to programmed death, and relative immortality, driving tumor diversity and treatment variability.
Public health
fromBusiness Matters
1 month ago

Chronic Disease Prevention Remained Abstract for Too Long - Barbara Mkhitarian Made It Measurable

Digital prevention programs combining nutrition coaching with behavioral psychology achieve average 7 kg weight loss and sustained diabetes risk reduction through evidence-based lifestyle intervention.
Science
fromwww.mercurynews.com
1 month ago

New Stanford study points to vaccine that protects against multiple infections

A single vaccine that activates innate immunity provided mice broad protection against respiratory viruses, bacteria, and allergens, representing a new vaccination approach.
Mental health
fromPsychology Today
2 months ago

Global Study Identifies Genetic Links to Depression

Genetic analyses have identified hundreds of variants linked to depression and revealed existing non-psychiatric drugs as potential treatment candidates.
Philosophy
fromPsychology Today
2 months ago

Can Accepting Our Biological Heritage Improve the World?

Biological imperative centers on protecting, promoting, and propagating genetic code, shaping behavior, sex-specific roles, physiology, and intergenerational wellbeing.
Public health
fromTruthout
1 month ago

Public Health Agencies Struggle to Keep Up With Rising Tuberculosis Cases

Tuberculosis cases and containment costs are rising nationwide, with Johnson County, Iowa experiencing a tripling of latent infections and costs surging from $17,000 to $65,000 annually, while state funding for contact tracing has been withdrawn.
fromNature
2 months ago

Daily briefing: Why 'harmless' germs can be deadly for some people

DNA variants near a gene called MSRB3 - which is important for hearing in humans - could determine whether a dog's ears are pendulous like a basset hound's or stubby like a rottweiler's. Researchers analysed the genomes of thousands of canines and found that small, single-letter changes to DNA in a region of the genome near MSRB3 could boost the gene's activity. The boost can increase the rate at which ear cells proliferate, resulting in longer ears.
Science
Mental health
fromPsychology Today
1 month ago

The Effect of Family History on Brain Injury

Knowing one’s family history and cultural roots is essential to reclaim identity, process grief, and repair relationships after catastrophic brain injury.
Science
fromNature
2 months ago

How ageing harms the body's response to raging infection

Some genes that protect against infection in young mice increase mortality in old mice by altering organ-specific immune endurance.
Medicine
fromenglish.elpais.com
1 month ago

The very long road from a cancer cure' in mice to one in humans

Promising mouse cancer cures often fail to become safe, effective human drugs; premature media claims can create false patient expectations and hinder responsible research progress.
Science
fromwww.scientificamerican.com
2 months ago

How long you live may depend much more on your genes than scientists thought

Heritability of human lifespan roughly doubles to about 50% when extrinsic mortality is removed, showing a stronger genetic influence on intrinsic aging.
Mental health
fromPsychology Today
2 months ago

Very Different Psychiatric Diagnoses Share Common Genes

Alcohol, cannabis, opioid, and nicotine use disorders share substantial genetic liability and cluster together as a single brain disorder, supporting a unified addiction-liability.
#obesity
Medicine
fromNature
2 months ago

The infection enigma: why some people die from typically harmless germs

Genetic mutations in immune-related genes cause inborn errors of immunity that make some people uniquely vulnerable to severe infections and immune disorders.
fromNews Center
1 month ago

Targeting Cellular Mechanisms May Improve Immune Response in Chronic Infections - News Center

During viral infection and in the case of cancer, CD4+ helper T-cells release cytokines, or small signaling proteins, that activate and "give permission" to other immune cells to control and clear viral pathogens. In certain viral infections, such as lymphocytic choriomeningitis virus (LCMV), which is spread by infected rodents, CD4+ T-cells differentiate into different subpopulations, including one subset of progenitor CD4+ T-cells that replenish type 1 helper (Th1) and follicular helper (Tfh) T-cells.
Science
Science
fromwww.scientificamerican.com
2 months ago

The bacterium behind syphilis has a far more ancient history than we thought

Treponemal diseases, including syphilis, originated much earlier than thought; a 5,500-year-old Treponema pallidum genome from Colombia pushes back their evolutionary timeline.
#cancer-prevention
Medicine
fromwww.dw.com
1 month ago

How the Epstein-Barr virus triggers MS in some people

Epstein-Barr virus infection combined with specific genetic factors can trigger multiple sclerosis by provoking immune attacks on myelin.
Science
fromNature
2 months ago

Huge Chinese cell atlas reveals surprising immune variation among peoples

Multi-omic atlas of immune cells from 428 Chinese individuals reveals population-specific immune-cell functions and genetic associations distinct from European and Japanese cohorts.
Medicine
fromThe Atlantic
1 month ago

Their Mutated Genes Were Supposed to Be Harmless

People who carry single-gene mutations for disorders like thalassemia can experience real health effects, including lethargy and fainting, despite being labeled asymptomatic.
Science
fromScienceDaily
2 months ago

Vitamin A may be helping cancer hide from the immune system

Retinoic acid signaling in cancer cells and dendritic cells suppresses anti-tumor immunity, and blocking this pathway restores vaccine effectiveness.
Public health
fromScienceDaily
2 months ago

A little-known health syndrome may affect nearly everyone

Nearly 90% of U.S. adults have CKM risk factors linking heart, kidney, and metabolic problems, raising risk of heart attack, stroke, and heart failure.
Public health
fromMail Online
2 months ago

Scientists discover 38% of cancers are caused by 30 lifestyle habits

Thirty-eight percent of global cancers in 2022 were attributable to 30 modifiable risk factors, so over one in three cases could be prevented.
Medicine
fromwww.theguardian.com
2 months ago

Positive thinking could boost immune response to vaccines, say scientists

Activating the brain's reward system (ventral tegmental area) through positive expectations enhances antibody responses to vaccination in humans.
fromwww.bbc.com
2 months ago

Trial launched to 'help spot health risks early'

Public health consultant Dr Ross Keat said supporting people earlier to make small preventative changes would make "a big difference later on". Some 3,500 people in the north of the island within that age bracket are eligible for the checks. The checks will be carried out by two pre-existing nurses that support GP staff and would not replace GP appointments, Keat explained, adding that the cost would be minimal and absorbed by Ramsey Group Practice.
Public health
fromNature
2 months ago

Exposome studies can improve lung health

The conventional approach to evaluating the impact of air pollution is to focus on a single exposure during a fixed period of time. But evidence suggests that contaminants work together, magnifying the damage to people's lungs. Conventional studies fail to probe synergistic effects. They also ignore the cumulative effects of lifelong exposures to pollutants, known as the exposome. Researchers need to shift away from single-pollutant studies and towards those involving a broad range of exposures.
Public health
Public health
fromwww.scientificamerican.com
1 month ago

Key NIH research institute told to remove references to 'pandemic preparedness'

NIAID staff were ordered to remove 'biodefense' and 'pandemic preparedness' from web pages as the institute shifts focus away from those research priorities.
Medicine
fromNews Center
2 months ago

Investigating HIV's Hidden Immune Evasion Strategy - News Center

HIV rewires infected cells' glycosylation to display sialoglycans that engage Siglec checkpoints, cloaking cells and suppressing immune clearance; targeted sialidase restores immune killing.
fromLGBTQ Nation
2 months ago

The amazing cases of 9 people "cured" of HIV each contain clues about a possible cure - LGBTQ Nation

For more than a decade, doctors and researchers have announced that a handful of people around the world have been cured of HIV. Each of these patients has experienced long-term viral control - in some cases for over a decade - without antiretroviral therapy (ART), as AIDSMap notes, though some doctors describe them as being in "remission." While the patients have shown no signs of HIV since stopping ART, at least some uncertainty remains as to whether the virus could eventually rebound in them.
Medicine
Public health
fromwww.scientificamerican.com
2 months ago

A shadow CDC' is scrambling to fill gaps in public health data

CDC authority and data reporting have collapsed due to leadership changes and cuts, leaving vaccine-related datasets paused and states forming alliances to fill public health gaps.
Medicine
fromPsychology Today
2 months ago

The Compelling History of a Disease Basis for Mental Illness

Psychiatry pursued brain-disease explanations for mental disorders, driven by medicine's historical emphasis on physical disease, despite lack of definitive brain-disease findings this century.
Public health
fromNature
2 months ago

Will mpox go global again? Research shows it's evolving in curious ways

Mpox is evolving, caused a major 2022 global outbreak, can persist in mice testes suggesting potential male fertility impact, and risks vaccine or treatment evasion.
fromHarvard Gazette
2 months ago

Real-world answers for patients running out of time - Harvard Gazette

But these studies typically require large numbers of patients, huge amounts of data, and thorough follow-ups, none of which comes easy or free. The upshot is fewer investigations into scenarios that are clinically important but unlikely to yield a profit for the firms funding them. Accordingly, researchers have been developing an option that uses real-world data from insurers to save patients from falling through the cracks.
Medicine
fromwww.theguardian.com
2 months ago

The sudden rise of scabies: I wouldn't wish it on my worst enemy'

Clothes, toothbrushes, hairbrushes, a teddy Although it should be two teddies, she re-evaluates, quickly. I can hear her trying to quell her panic. A diehard survivalist preparing for catastrophe? Actually, a beleaguered 44-year-old mother recovering from scabies an itchy rash caused by microscopic mites that burrow under human skin. Far-fetched as it sounds, emergency evacuation is exactly what she, her partner and children (six and four) resorted to in November in a desperate bid to beat the bugs.
Public health
from48 hills
2 months ago

The US fails again to fix the real causes underlying poor health - 48 hills

If you're smoking three packs of cigarettes a day, should you expect society to pay when you get sick?" He added that while Americans would always have the right to "eat donuts all day," nevertheless, "should you then expect society to care for you when you predictably get very sick at the same level as somebody who was born with a congenital illness?
Public health
Public health
fromwww.npr.org
1 month ago

TB or not TB? That is the question

Approximately 1 million TB false negatives and over 2 million false positives occur annually, causing mistreatment and missed serious alternative diagnoses.
#measles
Public health
fromNature
2 months ago

Nationwide genetic screening proves effective at catching disease risk early

Early genetic screening in young adults can identify hereditary cancer and familial hypercholesterolaemia risk before symptoms, but generalizability and cost-benefit require evaluation.
fromwww.independent.co.uk
2 months ago

Top preventable cancer causes in UK revealed and how to cut your risk

Smoking, being overweight, and exposure to ultraviolet radiation from the sun and sunbeds are the top preventable causes of cancer, experts have warned. Researchers from the World Health Organisation (WHO) and its International Agency for Research on Cancer (IARC) analysed 30 risk factors that cause cancer, such as smoking, drinking alcohol and air pollution. Using data from across 185 countries, they estimate that about 7.1 million of the 18.7 million new cancer cases diagnosed globally in 2022 were preventable.
Public health
Public health
fromNature
2 months ago

Making progress on global health will need high-quality evidence

Nature Health will prioritize research that bridges the gap from health research to policy and practice, emphasizing real-world impact and resource-limited settings.
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