#genetic-factors

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#genetics
Medicine
fromNews Center
3 days ago

Uncovering a Genetic Driver of Rare Early-Onset Dementia - News Center

A new genetic risk factor for early-onset frontotemporal dementia has been identified, significantly increasing the odds of developing the disease.
#genomics
fromNature
4 days ago
Science

The 1000 Chinese Pangenome empowers medical and population genetics - Nature

fromNature
4 days ago
Science

The 1000 Chinese Pangenome empowers medical and population genetics - Nature

LGBT
fromPsychology Today
5 days ago

Why Identical Twins Can Have Different Sexual Orientations

Sexual orientation may have genetic links, but identical twins can have different orientations due to epigenetics and prenatal hormone exposure.
#crispr
fromNature
1 week ago

Can a mouse be cloned indefinitely? Decades-long experiment has answers

Asexual reproduction is ultimately unsustainable for mice, and potentially other mammals, too. The clones looked normal and lived as long as normal mice. But large mutations - including the loss of an entire chromosome - accumulated in the cloned lineage at an unusually high rate.
OMG science
Science
fromNature
2 weeks ago

Synthetic circuits for cell ratio control - Nature

Synthetic biology enables artificial cell differentiation and division of labor by engineering genetic and epigenetic circuits that mimic natural stem cell asymmetric division processes.
Health
fromInsideHook
3 weeks ago

Medical Experts Recommend a Genetic Test for Heart Disease Risk

The American Heart Association and American College of Cardiology now recommend genetic testing for lipoprotein(a) to identify heart disease risk factors unaffected by diet and lifestyle changes.
Mental health
fromPsychology Today
1 month ago

A Genetic Map Redrawing the Borders of Mental Illness

Five broad genetic families underlie 14 psychiatric disorders, suggesting diagnostic categories reflect shared biological landscapes rather than distinct diseases.
Cancer
fromenglish.elpais.com
1 month ago

Three sisters and a dilemma: what to do when you inherit a genetic mutation that can cause cancer

Three sisters discovered they carry the BRCA1 gene mutation, which significantly increases breast and ovarian cancer risk, after their cousin's rapid cancer diagnosis prompted family genetic testing.
Medicine
fromNature
1 month ago

Identical twins on trial: can DNA testing tell them apart?

Identical twins share identical DNA, making standard forensic DNA testing unable to distinguish which twin committed a crime, though whole-genome sequencing can identify rare post-birth mutations to differentiate them.
Science
fromNature
1 month ago

Daily briefing: How DNA testing can tell identical twins apart

Advanced forensic techniques including whole-genome sequencing and epigenetic analysis can differentiate between identical twins in criminal investigations, while GLP-1 drugs show potential in reducing addiction across multiple substances, and researchers have successfully synthesized hexagonal diamond.
Left-wing politics
fromTruthout
1 month ago

Reproductive Tech That Promises Smart Babies Is Peddling Soft Eugenics

Reproductive tech companies now offer embryo genetic screening for intelligence and disease, raising concerns about eugenics, disability discrimination, and wealth-based genetic enhancement.
fromwww.theguardian.com
1 month ago

I clicked on a button and everything changed': how a DNA test turned my life upside-down

It was another detail that the rest of the family apparently knew but had never told me; they thought I already knew. The biology mattered less to me than the secret. Dad had been adopted, it turned out. A classic affliction of the 1950s, in which young, unmarried couples were forced to give away their newborn babies.
Books
OMG science
fromNature
1 month ago

Daily briefing: This Utah family line might be evidence of 'selfish genes' in humans

Researchers identified a Utah family with seven generations showing twice as many boys as girls, providing first clear evidence of sex-ratio distorting genes in humans.
fromwww.nature.com
1 month ago

Genetically encoded assembly recorder temporally resolves cellular history

GEMINI leverages a computationally designed protein assembly as an intracellular memory device to record the history of individual cells. GEMINI grows predictably within live cells, capturing cellular events as tree-ring-like fluorescent patterns for imaging-based retrospective readout. Absolute chronological information of activity histories is attainable with hour-level accuracy.
fromNature
1 month ago

Is a 'selfish gene' making a Utah family have twice as many boys as girls?

Such sex 'distorters' have been discovered - and studied in great depth - in laboratory animals such as mice and flies, in which their effects can be detected through selective breeding. 'If you look, more often than not, you find them,' says Nitin Phadnis, an evolutionary geneticist at the University of Utah in Salt Lake City, who co-led the study.
Science
Science
fromInsideHook
1 month ago

Scientists Question the Conventional Y Chromosome Wisdom

Researchers discovered evidence that certain genetic elements can skew sex ratios toward male offspring beyond the expected 50/50 split, with one family showing a 2:1 male-to-female ratio across generations.
Medicine
fromThe Atlantic
1 month ago

Their Mutated Genes Were Supposed to Be Harmless

People who carry single-gene mutations for disorders like thalassemia can experience real health effects, including lethargy and fainting, despite being labeled asymptomatic.
Public health
fromNature
2 months ago

Nationwide genetic screening proves effective at catching disease risk early

Early genetic screening in young adults can identify hereditary cancer and familial hypercholesterolaemia risk before symptoms, but generalizability and cost-benefit require evaluation.
Philosophy
fromAeon
2 months ago

Groundbreaking visuals capture how our bodies repair damaged DNA | Aeon Videos

Drew Berry creates striking biomedical animations that visualize microscopic biological processes like DNA repair, revealing intricate evolution-shaped cellular mechanisms.
Psychology
fromPsychology Today
1 month ago

Twin Studies and the Role of Genetics in Religious Belief

Parental upbringing shapes childhood religious participation, while genetic factors influence adult religious interest and involvement; identical twins can show strong similarity even when reared apart.
Board games
fromBoard Game Quest
2 months ago

Genotype: A Mendelian Genetics Game Review

Mendel's pea experiments underpin modern genetics, informing everyday genetic testing, debates over manipulation, and a game simulating Mendelian breeding and research.
fromNature
1 month ago

AI tools can design genomes. Will they upend how life evolves?

Biology is undergoing a transformation. After centuries of studying life as it evolves naturally, researchers are now using a combination of computation and genome engineering to intervene, generating new proteins and even whole bacteria from scratch. The use of artificial-intelligence tools to design biological components, an approach known as generative biology, is set to turbocharge this area of research. Just last year, scientists used AI-assisted design to produce artificial genes that can be expressed in mammalian cells.
Science
Mental health
fromPsychology Today
2 months ago

Very Different Psychiatric Diagnoses Share Common Genes

Alcohol, cannabis, opioid, and nicotine use disorders share substantial genetic liability and cluster together as a single brain disorder, supporting a unified addiction-liability.
Philosophy
fromPsychology Today
2 months ago

Can Accepting Our Biological Heritage Improve the World?

Biological imperative centers on protecting, promoting, and propagating genetic code, shaping behavior, sex-specific roles, physiology, and intergenerational wellbeing.
fromIrish Independent
1 month ago

Risk of carrying the 'Celtic curse' gene varies across Ireland, new study finds

Targeting genetic screening for the condition to priority areas could help identify at-risk individuals earlier and avoid future health complications, experts say. Haemochromatosis symptoms can evolve over decades as high iron levels in the body cause damage to organs. Early diagnosis and treatment - such as regular blood donation to reduce iron levels - is key to prevent liver damage, liver cancer and arthritis.
Public health
fromArs Technica
1 month ago

Have we leapt into commercial genetic testing without understanding it?

Martschenko's argument is largely that genetic research and data have almost always been used thus far as a justification to further entrench extant social inequalities. But we know the solutions to many of the injustices in our world-trying to lift people out of poverty, for example-and we certainly don't need more genetic research to implement them. Trejo's point is largely that more information is generally better than less.
Science
Mental health
fromPsychology Today
2 months ago

Global Study Identifies Genetic Links to Depression

Genetic analyses have identified hundreds of variants linked to depression and revealed existing non-psychiatric drugs as potential treatment candidates.
Science
fromwww.scientificamerican.com
2 months ago

How long you live may depend much more on your genes than scientists thought

Heritability of human lifespan roughly doubles to about 50% when extrinsic mortality is removed, showing a stronger genetic influence on intrinsic aging.
Science
fromNature
2 months ago

Construction of complex and diverse DNA sequences using DNA three-way junctions - Nature

DNA writing remains limited by short oligo synthesis and two-way junction assembly methods, hindering affordable, scalable construction of large, complex synthetic DNA.
Science
fromwww.nature.com
2 months ago

Scalable and multiplexed recorders of gene regulation dynamics across weeks

CytoTape enables multiplexed, genetically encoded, spatiotemporally scalable recording of gene regulation dynamics in single cells for up to three weeks with minute-scale resolution.
Science
fromSilicon Canals
1 month ago

This gene mutation on chromosome 11 is why cilantro tastes like dish soap to millions of people - Silicon Canals

Genetic variation in the OR6A2 receptor causes cilantro to taste like soap to some people by detecting aldehyde compounds present in the herb.
fromNature
2 months ago

Daily briefing: The human cells in our bodies that aren't genetically ours

A virus that sickens marine mammals has been detected in Arctic waters for the first time. Scientists used drones armed with petri dishes to collect samples of blow - the air and mucus whales expel from their blowholes - from whales in northern Norway. The team identified cetacean morbillivirus in samples from humpback whales ( Megaptera novaeangliae) and one sperm whale ( Physeter macrocephalus), though the humpbacks showed no symptoms of disease.
Science
Science
fromNature
2 months ago

An expanded registry of candidate cis-regulatory elements - Nature

The cCRE registry expanded to 2.37 million human and 967,000 mouse elements and integrates functional characterization for over 97% of human cCREs.
Science
fromWIRED
2 months ago

He Went to Prison for Gene-Editing Babies. Now He's Planning to Do It Again

He Jiankui created the first gene-edited babies, was jailed and banned, and now seeks to resume controversial genetic research despite widespread germline-editing prohibitions.
Science
fromNature
2 months ago

Developmental convergence and divergence in human stem cell models of autism - Nature

Distinct rare mutations and common genetic variation jointly shape ASD risk, yet convergent molecular pathology and early fetal neurodevelopmental mechanisms can be studied using stem-cell models.
Science
fromNews Center
2 months ago

New Underlying Mechanisms May Support Proper Transcriptional Regulation and Improve - News Center

New mechanisms controlling transcription initiation and elongation involving BET family proteins were identified, revealing pathways that could enable improved targeted therapies for diseases including cancer.
Science
fromNature
2 months ago

A 'time capsule for cells' stores the secret experiences of their past

Engineered TimeVaults capture and store cellular mRNA to continuously record past transcriptional activity, enabling retrospective study of cellular history and responses.
Science
fromNews Center
2 months ago

Understanding the Link Between Nucleotide Metabolism and Chromatin Assembly - News Center

PRPS enzymes coordinate nucleotide synthesis and early histone maturation, synchronizing DNA replication and chromatin assembly through dual metabolic and regulatory roles.
fromFuturism
1 month ago

Jeffrey Epstein Had a Bizarre Obsession With "Improving" Human DNA, and He Was Emailing With Top Scientists About It

The newly released documents from the Justice Department shine additional light on how the convicted child sex criminal exhibited a fascination with transhumanism, a controversial movement in science and philosophy with a eugenicist mission: using cutting edge technology, including genetic engineering and AI, to advance the biology of the human race. They also reinforce how serious Epstein was about pursuing these ideas.
Science
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