#lupus-nephritis

#lupus-nephritis

"This argues for the need to sustain such policies and shows that it is possible to right the wrongs retroactively, which is a powerful idea," said Kenneth Michelson, MD, MPH, associate professor of Pediatrics in the Division of Emergency Medicine and a co-author of the study.

C4b-binding protein (C4BP) was identified as the missing cofactor that allows anti-phosphatidylethanolamine (aPE) antibodies to exert their damaging effects, linking them to thrombosis and pregnancy complications.

We knew that if you inject these nanoparticles into an animal model, the nanoparticles get taken up by antigen presenting cells and this resulted in increased regulatory T-cells and decreased inflammatory disease. However, we did not know how this happens,