#sudep

#sudep

The condition, called recessive RNU2-2-related neurodevelopmental disorder, is associated with seizures and severe developmental delay in children less than a year-old, in areas such as speech and walking.

When Lorraine Kelly Donnelly felt a cramp in her left hand at the start of 2025, she didn't think anything of it. But when a week later the pain was still there, she made an appointment to see her GP.

There is a piece of advice given to doctors in moments like this: Check your own pulse. Each person in the room has a role, and we perform it best with steady hands and measured voices.

Mark McNamee said, 'I still can't get my head around it. For just a simple ear infection to basically, it's nearly destroyed your life for you.'

In each of the past three years in the county, three to five infants have died in their sleep. That's down from 10 such deaths in 2022 but it's a number that could spike again this year or next.

From reproductive rights to climate change to Big Tech, The Independent is on the ground when the story is developing. Whether it's investigating the financials of Elon Musk's pro-Trump PAC or producing our latest documentary, 'The A Word', which shines a light on the American women fighting for reproductive rights, we know how important it is to parse out the facts from the messaging.

From reproductive rights to climate change to Big Tech, The Independent is on the ground when the story is developing. Whether it's investigating the financials of Elon Musk's pro-Trump PAC or producing our latest documentary, 'The A Word', which shines a light on the American women fighting for reproductive rights, we know how important it is to parse out the facts from the messaging.

It arose out of safety concerns in 2022 in relation to the treatment of a number of patients with Spina Bifida who had spinal surgery at CHI at Temple Street. These concerns related to poor clinical outcomes of some complex spinal surgery, including a high incidence of post-operative complications and infections, and two particularly serious surgical incidents, which occurred in July and September 2022.

Studies suggest nearly 60 percent of people with OSA experience some degree of cognitive impairment, including difficulties with attention, working memory, and episodic memory. Mood disorders such as depression and anxiety are also more common. Over time, untreated sleep apnea has been linked to declines in concentration, executive function, and long-term memory. So what's actually happening inside the brain while someone with undiagnosed sleep apnea sleeps?

Mucopolysaccharidosis type II (MPS II), or Hunter syndrome, is a rare genetic disorder primarily affecting boys, caused by a deficiency in the enzyme needed to break down sugar molecules. This harmful buildup in cells and tissues impacts multiple body systems, causing frequent infections, organ enlargement and developmental disabilities. Management involves supportive care and enzyme replacement therapy, as there is currently no cure,