#uptake-rates

#uptake-rates

On that sunny March morning, in a small health center in Lobamba, a rural area of Eswatini, this 32-year-old sex worker has just become one of the first people in the world to receive lenacapavir, a drug that, administered twice a year, offers nearly 100% protection against HIV.

Incyte tops this list due to its rare combination of commercial scale, cash generation, and pipeline depth. The company posted FY2025 revenue of $5.14 billion, up 21.2% YoY, anchored by Jakafi generating $828.2 million in Q4 2025 alone (+7% YoY) and Opzelura delivering $207.3 million (+28% YoY). With $3.58 billion in cash and 14 pivotal clinical trials underway, Incyte offers an acquirer immediate revenue, margin expansion potential, and a deep oncology pipeline spanning KRASG12D, CDK2 inhibition, and mutCALR.

"This argues for the need to sustain such policies and shows that it is possible to right the wrongs retroactively, which is a powerful idea," said Kenneth Michelson, MD, MPH, associate professor of Pediatrics in the Division of Emergency Medicine and a co-author of the study.

Kelly Chibale describes the drug discovery process as a fairy-tale quest, stating, 'It doesn't mean that there aren't surprises or miracles. They do happen, but you have to kiss many frogs before you meet the prince.' This metaphor illustrates the challenges and unpredictability in finding effective medicines.

I am open-minded; I believe in integrative practices, and I agree that the medical establishment can be arrogant and unduly influenced by the pharmaceutical industry, which now funds so much of medical research. But I fully understand Scherer's frustration with his interminable discussions with Kennedy about scientific articles.

Trish Mannes stated, "this peak has passed, absolutely" but cautioned that cases could still arise, emphasizing the need for ongoing monitoring.

Emma Dyer remembers the moment she clicked "buy now" on a set of weightloss jabs she found online. She had no medical consultation, no ID checks, and no questions about her history of anorexia and bulimia. "It was just so easy - too easy," she says. "They never asked for my medical history or what medication I was taking. It was like buying groceries."

The World Health Organization announced in late January that six European countries: the United Kingdom, Spain, Austria, Armenia, Azerbaijan and Uzbekistan had all officially lost their measles elimination status, which means the virus has been circulating continuously in those countries for more than 12 months.

Between March 2020 and March 2022, over 100 million telemedicine services were delivered to approximately 17 million Australians. The Australian government invested $409 million to make telehealth permanent, whilst the UK announced £600 million for digital health infrastructure in April 2025. Patient adoption is equally impressive: 60% find telemedicine more convenient than in-person appointments, 55% report higher satisfaction with teleconsultations, and 74% of millennials prefer virtual appointments for routine care. These aren't temporary shifts; they represent a fundamental transformation in healthcare delivery.

The cancer was fastacting, and if I'd left it even six months, the outcome could have been much worse,

"What we've identified here could help improve adherence to vaccination quicker if we target the right people," he says.

Eduardo Vilar-Sanchez has spent more than 10 years pursuing a goal that seemed very distant, but which he now sees as a little closer: to develop a preventive vaccine against cancer. The physician and researcher is leading a study that presented the first promising results of a colon cancer vaccine in a small group of patients suffering from a rare disease that makes them 17 times more likely to develop colon cancer than the general population.

In 2026, the US healthcare system is changing. Enhanced Affordable Care Act subsidies have expired, causing premiums for marketplace plans to spike - and pricing some families out of health insurance entirely. President Donald Trump's One Big Beautiful Bill Act will reduce coverage for some patients with Medicaid and funding for hospitals, especially those in rural areas. Costs for Medicare and private insurance are also rising: Employer-based healthcare premiums have increased by 9%, the largest rise in more than a decade.

In many ways, public health can't afford to ignore gamification. Addiction is already gamified-and it's winning. As one example, "smart" vapes now feature screens, rewards, animations, and puff tracking. These high-tech devices have become top-selling products, with 32% of youth and 33% of young adults reporting using vapes with screens, games, or Bluetooth connectivity in the past month. These products are applying the same engagement strategies used in consumer tech to drive repeat use and ultimately sustain addictive behavior.

Public health consultant Dr Ross Keat said supporting people earlier to make small preventative changes would make "a big difference later on". Some 3,500 people in the north of the island within that age bracket are eligible for the checks. The checks will be carried out by two pre-existing nurses that support GP staff and would not replace GP appointments, Keat explained, adding that the cost would be minimal and absorbed by Ramsey Group Practice.

Perhaps the most significant milestone was the adoption by WHO Member States of the Pandemic Agreement, a landmark step towards making the world safer from future pandemics. Alongside this, amendments to the International Health Regulations came into force, including a new pandemic emergency alert level designed to trigger stronger global cooperation. And to sustainably finance the WHO's work, governments in a historic show of support increased their contributions to our core budget.

Adult literacy advocate Toni Cordell recounts the story of feeling comforted when her doctor told her that her medical concern could be solved with an easy surgery. She agreed to proceed without asking further questions and didn't understand the medical consent forms because she didn't read well. At a follow-up office visit a couple of weeks after the procedure, Cordell was shocked when the nurse asked, "How are you feeling since your hysterectomy?"

In 2021, amid the COVID‑19 pandemic, Kristin Wall became pregnant with her second child. Her physician told her that little was known about the COVID-19 vaccine's safety and effectiveness in pregnant people. Observational data - collected from those vaccinated before they knew that they were pregnant - suggested that the vaccine was safe, so she could have it. Still, she'd have to weigh up the risks and benefits herself.

Half a world away, specialists in Japan say they have some hard-won wisdom to offer. They watched flu and pneumonia deaths spike after the Japanese government stopped pushing parents to have their children vaccinated against influenza. They witnessed rubella outbreaks driven by shifting vaccine guidance that left a segment of the population vulnerable. And they saw an unfounded media scare turn the public away from immunizations against human papillomavirus (HPV), which is responsible for nearly all cases of cervical cancer.