The INLIGHT interim readout reported a 14.3% placebo-adjusted reduction in visceral fat six months after a single dose, alongside preservation of lean muscle mass - a differentiated profile compared to GLP-1 therapies that often reduce muscle alongside fat.
Most of the carbohydrates in these foods - as well as most of the calories - come from starch, of which there are two types: hard-to-digest amylose and easily digested amylopectin. The latter is processed quickly and spikes blood sugar. The former is processed slowly and moderates blood sugar.
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Emma Dyer remembers the moment she clicked "buy now" on a set of weightloss jabs she found online. She had no medical consultation, no ID checks, and no questions about her history of anorexia and bulimia. "It was just so easy - too easy," she says. "They never asked for my medical history or what medication I was taking. It was like buying groceries."
In the mid-1990s, child mental health researchers at top New York institutions injected grade-school boys with fenfluramine, also known as the diet drug "fen-fen," a substance that was later banned by the Food and Drug Administration, due to its links to valvular heart disease and pulmonary hypertension. The boys were all Black or Hispanic by design: Eligible participants were required to be African American or Hispanic because they were deemed to be at higher risk for developing disruptive behaviors.
A Colorado endocrinologist helped spark a quiet revolution in weight care by changing how primary care clinics talk about - and treat - obesity. Instead of vague advice to "eat less and exercise more," a new system called PATHWEIGH gave patients a clear, judgment-free path to real medical support for weight management.
"I can't tell you how many times I've had patients who have had so much trouble losing weight complain to me that their friends can eat whatever they want and never put weight on," Perlman, an integrative and functional medicine doctor and former chief medical officer for Mayo Clinic's integrative medicine program, told Business Insider. It's also one of the biggest misconceptions he hears about metabolic health.
