We've created a small molecule chemical which gets in your body very well. It can mimic the effects of the peptide and can be taken more conveniently any time of day without any food or water restrictions.
Tyburski was a professional adventurer, financing his pursuits via magazine articles and speaking gigs, and even making a documentary about his quest. His whole raison d'etre was to push past his limitations, showing what a person is capable of when their mindset is strong enough.
It's not simply the accrual of excess fat that leads to disease. It's a change in the actual function and the capacity of the energy center within the cell to work properly. The circadian rhythm is the body's own internal 24-hour clock that regulates the sleep-wake cycle, hormone levels and metabolism, among other systems throughout the body.
I grew up in a Mexican household where food was our love language - but there was also stigma and very little guidance around diabetes. When my aunt, and later my mom, were diagnosed, it took time to understand what healthy eating could look like for them. That's why this partnership means so much to me. Our culture and our food are not the problem - they're part of the solution.
Most of the carbohydrates in these foods - as well as most of the calories - come from starch, of which there are two types: hard-to-digest amylose and easily digested amylopectin. The latter is processed quickly and spikes blood sugar. The former is processed slowly and moderates blood sugar.
As hormones shift during the transition into menopause, many women notice that their energy levels react differently to carbohydrates than they did in earlier years. Muscle mass tends to decline with age when strength training is absent from a routine. Because muscle mass determines how the body uses glucose, maintaining it through regular activity may support steadier daily energy.
By following more than 100,000 people in the U.K. for years, researchers found that people whose food choices scored high in any one of five diet categories tended to live longer than people who scored the lowest. Specifically, the team found that even after adjusting for confounding factorssuch as whether people smoked, how much exercise they took and what their education and ethnicity wasstudy participants who tended to eat according to any one of the five diets were 18 to 24 percent less likely to die of any cause. For women, that roughly translated into an extra 1.5 to 2.3 years of life. And for men, it added about 1.9 to three years.
Rather than simply extending the fasting window or cutting more calories, the intervention group was simply asked to finish eating at least three hours before their usual bedtime. That meant no snacking while watching TV after dinner and no "just one more bite" at 10 p.m. (my personal downfall). This relatively simple intervention ensured that the overnight fast overlapped with the body's natural sleep-wake rhythm.
You spent the year committed to regular workouts and cutting back on ultra-processed foods. Then came the holidays: a time of sedentary indulgence. "You're eating out of your comfort zone, and you're probably out of your fitness routine," Maddie Pasquariello, a registered dietitian in New York, told Business Insider. "Those things combined make people spiral."
We compared how participants fared while eating their habitual diets with how they responded to the two diets that were low in ultraprocessed foods. During the periods when participants ate fewer ultraprocessed foods, they naturally consumed fewer calories and lost weight, including total and abdominal body fat. Beyond weight loss, they also showed meaningful improvements in insulin sensitivity, healthier cholesterol levels, fewer signs of inflammation, and favorable changes in hormones that help regulate appetite and metabolism.
January might be coming to a close, but the focus on wellness doesn't have to die with it. If anything, it's a good time to check in with those 2026 goals and see what you want to prioritise for the rest of the year. To that end, we've gathered some of the best deals we've seen in the past few weeks that will help you tick off every good intention you set this month.
"I can't tell you how many times I've had patients who have had so much trouble losing weight complain to me that their friends can eat whatever they want and never put weight on," Perlman, an integrative and functional medicine doctor and former chief medical officer for Mayo Clinic's integrative medicine program, told Business Insider. It's also one of the biggest misconceptions he hears about metabolic health.
A Colorado endocrinologist helped spark a quiet revolution in weight care by changing how primary care clinics talk about - and treat - obesity. Instead of vague advice to "eat less and exercise more," a new system called PATHWEIGH gave patients a clear, judgment-free path to real medical support for weight management.
Intermittent fasting within an eight-hour window can significantly reduce symptoms of Crohn's disease, a new study has found. Crohn's disease, according to the NHS, is a long-term condition where part of the gut becomes inflamed. It cannot currently be cured and the common symptoms include: diarrhoea, blood or mucus in your poo and stomach pain. Researchers at the University of Calgary found that time-restricted feeding can reduce disease activity by 40 per cent and halve abdominal discomfort in over 12 weeks in people living with Crohn's disease.
Want to live longer but don't want to change what you're already doing to try and live a healthy life? We have good news. You likely don't need to spend an extra three hours in the gym every week. You also probably don't need to get eight hours of sleep every night. And you likely don't have to revamp your diet, either.
This opening episode dives straight into detoxing. From juice cleanses and detox teas to charcoal pills, foot pads, and coffee enemas, Edwards and Baumgardt watch, wince, and occasionally laugh their way through some of the internet's most popular detox trends. Along the way, they ask what these products claim to remove, how they supposedly work, and why feeling worse is often reframed online as a sign that a detox is "working."
