Some 1 million patients in the U.S. live with a type of heart disease called heart failure with preserved ejection fraction, or HFpEF, caused by a stiffening of a chamber of the heart that makes it much more challenging to distribute blood throughout the body. The condition has few approved therapies and high mortality rates.
A report last year found unnecessary surgeries were carried out, cancers were missed and poor standards of care were delivered at the University Hospital of North Durham and Darlington Memorial Hospital. CDDTF said it wanted to support the patients it had let down, including by offering access to psychological support, and to ensure they knew how to make a claim or raise concerns with police.
In many ways, public health can't afford to ignore gamification. Addiction is already gamified-and it's winning. As one example, "smart" vapes now feature screens, rewards, animations, and puff tracking. These high-tech devices have become top-selling products, with 32% of youth and 33% of young adults reporting using vapes with screens, games, or Bluetooth connectivity in the past month. These products are applying the same engagement strategies used in consumer tech to drive repeat use and ultimately sustain addictive behavior.
As the Magerstadt Professor of Cardiovascular Epidemiology, Khan studies the epidemiology of risk for heart failure. Using population-based cohorts and large electronic health record data analyses, she performs mechanistic studies that may enhance risk prediction and identify novel therapeutic agents for the prevention and treatment of cardiovascular disease. Khan and her team have developed a tool to predict risk and prevent cardiovascular disease such as heart failure, stroke, arrhythmia, coronary artery disease and many other conditions.
Evidence Based Medicine was formalized in the 1990s, largely by Canadian physician David Sackett. Sackett described the goal of EBM is to replace hunches and habits with data and clinical trials. Clinical guidelines were developed involving protocols that tell doctors which drug to prescribe first, what dose to use, when to escalate treatment, and when to refer a patient to a specialist.
In fact, last January, I decided to finally look at my macros - how much protein, fiber, carbs, and other nutrients I was actually eating. I've always tried to eat "healthy," but I was nervous about tracking anything too closely. I came of age during the clean-eating era, of salads, raw vegetables, and the demonization of carbs. In college, that slid into disordered eating: severe under-eating as a way to avoid "danger" foods.
Public health consultant Dr Ross Keat said supporting people earlier to make small preventative changes would make "a big difference later on". Some 3,500 people in the north of the island within that age bracket are eligible for the checks. The checks will be carried out by two pre-existing nurses that support GP staff and would not replace GP appointments, Keat explained, adding that the cost would be minimal and absorbed by Ramsey Group Practice.
You get sick from staying inside, breathing the same germ-filled air. Open your windows, even for five minutes, to circulate the old air out and let in fresh air. Also, if you're taking your child to the doctor, don't wait to treat their fever because you want 'the provider to see the fever.' Your child might wait two hours to be seen, meanwhile their temperature goes up, and they might have a seizure. If you say they've been having fevers, we believe you.
In 2021, amid the COVID‑19 pandemic, Kristin Wall became pregnant with her second child. Her physician told her that little was known about the COVID-19 vaccine's safety and effectiveness in pregnant people. Observational data - collected from those vaccinated before they knew that they were pregnant - suggested that the vaccine was safe, so she could have it. Still, she'd have to weigh up the risks and benefits herself.
On Tuesday the American Cancer Society (ACS) released its annual report on cancer statistics in the U.S., and it offered a rare bit of good news: the proportion of people who were alive at least five years after a cancer diagnosis hit a record high. The report found that, among all cancer patients diagnosed between 2015 and 2021 in the U.S., the survival rate at the five-year mark relative to those who didn't have cancer was 70 percent.
Nearly 40% of new cancer cases worldwide are potentially preventable, according to a new analysis. The study found that in 2022, smoking tobacco was the leading contributor to cancer cases, followed by infections and drinking alcohol. Reducing such risk factors is "one of the most powerful ways that we can potentially reduce the future cancer burden", says cancer epidemiologist and study co-author Hanna Fink.
Yes, there has been a shocking lack of progress in developing transformative psychiatric medicine (We need new drugs for mental ill-health, 5 February), but this may be because in mental health, drugs are not always the answer (see, for example, Richard P Bentall's Doctoring the Mind). Huge progress has been made in the effectiveness of talking therapies for example, free effective treatment for post-traumatic stress disorder (PTSD) is available to all UK army veterans through the charity PTSD Resolution.
But these studies typically require large numbers of patients, huge amounts of data, and thorough follow-ups, none of which comes easy or free. The upshot is fewer investigations into scenarios that are clinically important but unlikely to yield a profit for the firms funding them. Accordingly, researchers have been developing an option that uses real-world data from insurers to save patients from falling through the cracks.
Before treatment began, participants underwent neuroimaging. Instead of relying on a single modality, the researchers fused structural connectivity (how regions are physically wired) with functional connectivity (how regions co-activate at rest). The goal was not to throw every possible feature at a black box, but to learn a constrained pattern-what the authors call structure-function "covariation"-that carries the most predictive signal for outcome. In other words, the model tries to find the smallest set of connections that meaningfully forecasts symptom change.
Every day, many thousands of parents across the U.S. face the difficult question of whether to place their child or teenager on a psychotropic medication. Receiving a diagnosis of a mental disorder can be scary and confusing, for the youth as well as their parents/caretakers. What is ADHD? Depression? Anxiety? OCD? Bipolar? What are the available treatments? Do we have to use medications to treat the symptoms?
Dr. Elyse Stevens had a reputation for taking on complex medical cases, including people who'd been battling addiction for decades. Some were chronic-pain patients on high doses of opioids; others were sex workers and people living on the street. "Many of my patients are messy, the ones that don't know if they want to stop using drugs or not," said Stevens, a primary care and addiction medicine doctor.