"This argues for the need to sustain such policies and shows that it is possible to right the wrongs retroactively, which is a powerful idea," said Kenneth Michelson, MD, MPH, associate professor of Pediatrics in the Division of Emergency Medicine and a co-author of the study.
C4b-binding protein (C4BP) was identified as the missing cofactor that allows anti-phosphatidylethanolamine (aPE) antibodies to exert their damaging effects, linking them to thrombosis and pregnancy complications.
Some 1 million patients in the U.S. live with a type of heart disease called heart failure with preserved ejection fraction, or HFpEF, caused by a stiffening of a chamber of the heart that makes it much more challenging to distribute blood throughout the body. The condition has few approved therapies and high mortality rates.
"I can't wait to start taking care of patients," said Alison Almgren-Bell, who matched in internal medicine at McGaw Medical Center of Northwestern University. "They really have been my north star through all of medical training."
Our results are highly promising, especially since currently there are no approved treatments that address the underlying cause of Dravet syndrome. Since this gene regulation product targets the actual root cause of Dravet syndrome, we observed improvements in other developmental and cognitive symptoms, in addition to seizure control. This is unprecedented.
As the Magerstadt Professor of Cardiovascular Epidemiology, Khan studies the epidemiology of risk for heart failure. Using population-based cohorts and large electronic health record data analyses, she performs mechanistic studies that may enhance risk prediction and identify novel therapeutic agents for the prevention and treatment of cardiovascular disease. Khan and her team have developed a tool to predict risk and prevent cardiovascular disease such as heart failure, stroke, arrhythmia, coronary artery disease and many other conditions.
A new PhD track is being added to the Walter S. and Lucienne Driskill Graduate Program in Life Sciences ( DGP) for the 2026 application cycle, to enhance student learning and build community around computational biology and bioinformatics at Feinberg. The computational biology and bioinformatics (CBB) track in the graduate program will prepare students through coursework and lectures to use modern computational approaches, including machine learning and artificial intelligence, to extract biological insight from large-scale datasets to address complex biological problems.
The soft, flexible, robotic probe could dramatically improve safety during fetal surgeries, procedures in which physicians operate on a fetus before birth. Currently, doctors primarily rely on intermittent measurements of fetal heart rate using ultrasound imaging from outside the pregnant person's body. The new device, on the other hand, can be gently inserted through the same narrow port already used in fetal surgeries.
But these studies typically require large numbers of patients, huge amounts of data, and thorough follow-ups, none of which comes easy or free. The upshot is fewer investigations into scenarios that are clinically important but unlikely to yield a profit for the firms funding them. Accordingly, researchers have been developing an option that uses real-world data from insurers to save patients from falling through the cracks.
Mucopolysaccharidosis type II (MPS II), or Hunter syndrome, is a rare genetic disorder primarily affecting boys, caused by a deficiency in the enzyme needed to break down sugar molecules. This harmful buildup in cells and tissues impacts multiple body systems, causing frequent infections, organ enlargement and developmental disabilities. Management involves supportive care and enzyme replacement therapy, as there is currently no cure,
Baptist Health Sunrise will be the health network's most innovative hospital, featuring a unique layout, with a medical office building integrated into the hospital and a structure designed to accommodate growth. It will open with 100 inpatient beds, a 30-bed emergency department - and plenty of room to expand on its 26 acres of land. It also includes the latest technology - robotic surgical equipment and AI-enabled imaging.
Northwestern University has launched the Simpson Querrey Brain Health Institute (SQ-Brain), made possible by nearly $25 million in philanthropic funding from university trustee Kimberly K. Querrey ('22, '23 P). SQ-Brain envisions a future where our brains last as long as our bodies a world where brain health is continuously measurable, modifiable and monitorable across the lifespan, and where prevention of cognitive decline and brain injury is anchored in neurovascular biology and precision medicine.
A common diabetes medication does not help people with peripheral artery disease (PAD) and without diabetes walk farther, according to results from a major U.S. clinical trial published in JAMA. Peripheral artery disease (PAD) is a serious condition that affects blood flow to the legs, making walking painful and difficult. It impacts approximately 12 million adults in the U.S. and is linked to higher risks of heart attack and stroke.
AI plays an important role-but not by fixing fragmented data on its own. The work of organizing, connecting, and interpreting healthcare information still belongs to people and the systems they build. Where AI helps is after that foundation is in place: by bringing the right information forward at the right time, reducing the effort it takes to find what matters, and supporting better decisions in the moment of care.
My dad was in the emergency room, short of breath, chest tight, upper back aching. He looked pale and confused. An ultrasound showed excess fluid between his lung and chest wall. "We'll drain it," a resident said, as if he were unclogging a sink. For the next five days, thick, red-tinged fluid filled a plastic container beside my dad's hospital bed. Doctors sent his cells for "staining," a way to identify cancer. But no one used that word.