#rodent-experiments

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Medicine
fromPsychology Today
2 days ago

Building Wisdom With BDNF-and Ketamine

BDNF is crucial for brain health, and can be boosted through healthy habits and ketamine, aiding neuroplasticity and cognitive function.
fromNature
4 days ago

Dopaminergic mechanisms of dynamical social specialization - Nature

Social foraging strategies illustrate the balance between competition and cooperation, where individuals either produce resources or exploit the efforts of others, navigating ecological and social constraints.
Psychology
Science
fromNews Center
3 days ago

Uncovering Cellular Drivers of Increased Brain Signal Activity - News Center

High gamma activity in the brain is generated through complex mechanisms, impacting interpretations of neurological studies using this signal.
#rats
Pets
fromBig Think
4 days ago

How rats conquered Earth

Rats exemplify resilience and adaptability, having survived numerous global challenges and eradication efforts throughout history.
Exercise
fromFuturism
6 days ago

Scientists Intrigued by Microbe That That Makes Mice Swole

A gut microbe called Roseburia inulinivorans may enhance muscle strength and fitness, particularly in older adults.
Medicine
fromWIRED
2 days ago

A New Implant Aims to Rewire Stroke Patients' Brains

Epia Neuro aims to help stroke patients regain hand function using a brain implant and motorized glove.
#cloning
OMG science
fromFuturism
1 week ago

Scientists Cloned a Mouse, Then Cloned the Clone, Et Cetera. The Results Were Horrific

Cloning mice for 58 generations led to immediate death of offspring, revealing limits to mammalian cloning.
OMG science
fromNature
1 week ago

Can a mouse be cloned indefinitely? Decades-long experiment has answers

Asexual reproduction in mice is unsustainable due to accumulating mutations, limiting the potential for successful cloning.
OMG science
fromFuturism
1 week ago

Scientists Cloned a Mouse, Then Cloned the Clone, Et Cetera. The Results Were Horrific

Cloning mice for 58 generations led to immediate death of offspring, revealing limits to mammalian cloning.
OMG science
fromNature
1 week ago

Can a mouse be cloned indefinitely? Decades-long experiment has answers

Asexual reproduction in mice is unsustainable due to accumulating mutations, limiting the potential for successful cloning.
Psychology
fromPsychology Today
3 days ago

People Don't Just Update Beliefs, They Test Them

Understanding psychological change requires recognizing the role of control and mastery in actively pursuing change despite familiar limitations.
SF food
fromNature
1 week ago

Aversive learning hijacks a brain sugar sensor to consolidate memory - Nature

Nutrient sensors in the brain and digestive tract regulate appetite, feeding behavior, and cognitive processes related to memory and learning.
Philosophy
fromPsychology Today
1 week ago

'Animate': How Nonhuman and Human Minds Are Inherently Linked

Humans share traits with animals and have become disconnected, wrongly believing in our superiority over them.
Pets
fromPsychology Today
1 week ago

Dogs, Cats, and Other Nonhumans Are Not 'Just Animals'

A new book challenges speciesist narratives and promotes deeper respect for animals as sentient beings with powerful social bonds.
Productivity
fromFast Company
1 week ago

5 neuroscience-backed tips for beating procrastination

Cognitive overload, not procrastination, hinders progress on important projects, causing the brain to shift to survival mode and avoid challenging tasks.
Science
fromNews Center
1 week ago

Light Impacts How the Brain Perceives and Remembers Threats - News Center

Light influences how animals perceive threats and make risk avoidance decisions, impacting understanding of related human behaviors and disorders.
Medicine
fromwww.businessinsider.com
6 days ago

I'm a neurologist, and I don't think AI will make people dumber. Here's how to keep your brain sharp.

Neuroplasticity allows the brain to change and adapt at any age, influenced by environment, experiences, and cognitive challenges.
Science
fromNature
1 week ago

First atlas of brain organization shows development over a lifetime

Scientists created an atlas mapping brain connectivity patterns across the human lifespan, linking them to cognitive performance and potential developmental issues.
Psychology
fromPsychology Today
1 week ago

How to Think About the Brain

The brain operates through localization, with specific areas dedicated to distinct tasks, despite outdated and simplistic representations of its function.
OMG science
fromFuturism
2 weeks ago

Scientists Recruit Undergrad to Step Into Room Filled With Ravenous Mosquitoes for "Full-Body Massacre"

Georgia Tech's study reveals how mosquitoes select prey, demonstrating their behavior changes based on visual and chemical cues from targets.
Science
fromFuturism
2 weeks ago

Scientists Bring Mouse Brains Back to Life After "Cryosleep" Deep Freeze

Researchers are advancing towards cryosleep by restoring activity in mouse brains using vitrification, potentially aiding organ preservation and brain injury recovery.
Medicine
fromenglish.elpais.com
2 weeks ago

Why some people get hooked and others don't: genetics, childhood and brain circuits explain addiction

Addiction is a mental disorder requiring professional treatment, not a matter of willpower or personal choice, yet society continues to stigmatize it as a moral failing.
Philosophy
fromThe Conversation
3 weeks ago

What's it like to be a bat? Scientists develop new solution to the puzzle of animal minds

A new 'teleonome' framework evaluates animal welfare by understanding each species' evolutionary needs rather than isolated physiological measurements.
OMG science
fromwww.scientificamerican.com
2 weeks ago

Scientists built a tickle robot to solve one of biology's strangest mysteries

Neuroscientists use Hektor, a tickle robot, to systematically study the neurological and physiological mechanisms of ticklishness by measuring brain activity, facial expressions, heart rate, and other bodily responses.
US news
fromwww.npr.org
1 month ago

Scientists make a pocket-sized AI brain with help from monkey neurons

Scientists compressed an AI visual system model from 60 million to 10,000 variables while maintaining performance, revealing how biological brains achieve efficiency and potentially advancing both neuroscience and artificial intelligence.
Psychology
fromSilicon Canals
2 weeks ago

Neuroscience reveals that people who feel trapped in repetitive daily routines aren't lazy or unmotivated. Their dopamine system has downregulated to match the predictability, which means the routine didn't kill their motivation - it quietly rewired their brain to stop expecting anything worth anticipating. - Silicon Canals

Overly predictable routines suppress dopamine and motivation by eliminating the uncertainty that drives anticipation, causing emotional numbness despite external life satisfaction.
fromNature
2 weeks ago

Dopamine takes a hit: how neuroscience is rethinking the 'feel-good' chemical

Dopamine is one of the most extensively studied neurotransmitters, chemicals that convey signals from cell to cell. It's the one with the highest profile outside neuroscience: often known as the 'pleasure chemical', it's depicted as the hit of reward that people get from recreational drugs or scrolling through social media. That's a gross simplification of what dopamine does; on that, researchers agree.
Medicine
fromTheregister
2 weeks ago

Digital fruit fly brain model walks and cleans its feelers

The researchers at Eon Systems have taken several pre-existing components: a fruit fly brain scan, a tool for modelling neurons, a model of some of the fly's muscles and body, and a very simple virtual environment, connected them together and ran it. The team claims that the result displays some of the behavior of the real insect.
OMG science
Mental health
fromPsychology Today
1 month ago

A Genetic Map Redrawing the Borders of Mental Illness

Five broad genetic families underlie 14 psychiatric disorders, suggesting diagnostic categories reflect shared biological landscapes rather than distinct diseases.
Science
fromFuturism
2 weeks ago

Researchers Upload Fly's Brain to Matrix, Let It Control Virtual Body

Eon Systems created a computational model of a fruit fly's 125,000 neurons and 50 million synapses that exhibits multiple behaviors in a virtual environment with 95% accuracy in predicting motor behavior.
fromwww.theguardian.com
2 weeks ago

A petri dish of human brain cells is currently playing Doom. Should we be worried?

Cortical Labs in Melbourne taught a dish of lab-grown neurons to play Pong in 2022. Now it has built what it describes as the world's first code-deployable biological computer, running on living human tissue rather than silicon chips, which is happily playing the 1993 shooter Doom. At first it didn't know how to move, aim or shoot. Then it would shoot two enemies and stop. So it's definitely learning.
OMG science
Pets
fromBoston.com
1 month ago

A rat race to the rescue: MSPCA-Angell seeks homes after 163 rodents surrendered

MSPCA-Angell received 163 rats from a single surrender in Essex County, the largest in at least five years, with 53 available for adoption at their facilities.
#raccoon-cognition
fromFortune
2 months ago
Science

For 15 years, a neuroscientist has studied raccoon intelligence in Central Virginia. Then a drunk one passed out in a nearby liquor store | Fortune

fromFortune
2 months ago
Science

For 15 years, a neuroscientist has studied raccoon intelligence in Central Virginia. Then a drunk one passed out in a nearby liquor store | Fortune

fromwww.scientificamerican.com
3 weeks ago

The gut microbiome may influence brain aging, mouse study suggests

Young, two-month-old lab mice housed with older, 18-month-old mice showed really impaired cognition. Researchers exposed young mice raised in a sterile, microbe-free environment to gut bacteria from old mice, causing the younger animals to perform worse on cognitive tests, as if they had prematurely aged, just like the cohoused mice.
Medicine
#brain-stimulation
fromPsychology Today
3 weeks ago
Psychology

Can Brain Stimulation Make Us More Altruistic?

Synchronizing brain activity between frontal and parietal regions through electrical stimulation increases altruistic choices, particularly when personal costs are high.
fromwww.bbc.com
1 month ago
Science

Can a pulse of electricity to the brain make us less selfish?

Simultaneous electrical stimulation of frontal and parietal brain areas temporarily increases people's willingness to share money.
Psychology
fromPsychology Today
3 weeks ago

Can Brain Stimulation Make Us More Altruistic?

Synchronizing brain activity between frontal and parietal regions through electrical stimulation increases altruistic choices, particularly when personal costs are high.
Science
fromNature
3 weeks ago

Scientists revive activity in frozen mouse brains for the first time

German researchers successfully cryopreserved and thawed mouse brains while preserving some neuronal functionality using vitrification, advancing toward potential future applications in brain protection and organ banking.
OMG science
fromMail Online
3 weeks ago

Scientists solve the mystery of why cats always land on their feet

Cats' ability to land on their feet results from an exceptionally flexible thoracic spine that rotates nearly three times more than their lumbar spine, enabling rapid mid-air body reorientation.
fromMail Online
3 weeks ago

Incredible map reveals how the brain processes different emotions

They created an artificial 'mental map', with pleasantness along one axis and bodily reactions along the other, and charted how the brain responded while watching clips from films. The results revealed clear groupings in the way that our brains represent emotion - with guilt, anger and disgust in one corner and happiness, satisfaction and pride in the other.
Science
Psychology
fromWIRED
3 weeks ago

Left-Handed People Are More Competitive, Says Science

Left-handedness persists at stable 10% rates due to frequency-dependent evolutionary advantages in competitive situations, where left-handers' unpredictability provides strategic benefits that disappear if they become too common.
Science
fromwww.theguardian.com
3 weeks ago

Short films made from brain activity of mice aim to show how they see world

Scientists reconstructed pixelated movies from mouse brain activity to understand how animals perceive visual information, advancing knowledge of animal cognition and brain function.
fromPsychology Today
1 month ago

Could Glial Cells Be the Key to New Schizophrenia Treatments?

Anyone living with schizophrenia understands the true limitations of current treatment options. Antipsychotics remain the single leading treatment for the disorder, and they are riddled with undesirable side effects. Weight gain, tardive dyskinesia, and excessive drowsiness are a few. Much research is devoted to expanding the range of medication options, and few academics have pursued other avenues. However, there is a possibility that treatment for schizophrenia can be approached through cellular methods if long-term research validates early signs of hope.
Mental health
fromwww.nature.com
1 month ago

Shared neural substrates of prosocial and parenting behaviours

Mice with higher levels of parenting exhibit more prosocial allogrooming toward stressed adults. The medial preoptic area (MPOA), a brain area involved in parenting behaviour, bidirectionally regulates allogrooming toward stressed conspecifics. Allogrooming and parenting behaviours recruit a partially overlapping neuronal ensemble in the MPOA, are both controlled by an MPOAtoVTA pathway and are associated with dopamine release in the nucleus accumbens.
fromFast Company
1 month ago

Our brains are wired to ignore information. Here are neuroscience-backed tips for communicating memorably

The human brain is engineered to ignore most of what it sees and hears, according to the neuroscientists I interviewed for the audio original Viral Voices. If that's the case, how are you supposed to make a memorable impression? The empowering news is that if you understand how the brain works, what it discards, and what it pays attention to, you'll be far more persuasive than you've ever imagined. Persuasive people have influence in their personal and professional lives.
Philosophy
fromFuturism
2 months ago

Researchers Just Discovered Something Startling About How Conservatives Pick Political Positions

As it turns out, neuroscience might be able to explain why. In a new study whose findings will surprise absolutely no one who's endured a fiery holiday dinner debate, researchers discovered that conservative and liberal brains don't just arrive at fundamentally different conclusions, but take strikingly different paths to get there. It's a fascinating piece of research which just might explain something about the yawning political divides currently tearing society apart.
US politics
Mindfulness
fromPsychology Today
2 months ago

From Neurons to Networks

AI evolved into a psychological mirror that externalizes attention and imagination, challenging emotion, meaning, relational depth, and requiring mindfulness to preserve human agency.
Science
fromNature
1 month ago

This compound enhances long-term memory of mice - but only in females

Acetate, a metabolic by-product from alcohol, glucose, and fiber breakdown, enhances memory performance in female mice through histone acetylation in the hippocampus.
fromPsychology Today
2 months ago

If Punishments Don't Work, What Does?

First, you have to facilitate through the situation, which means realigning your mindset and asking yourself what you need to do to effect change for the next time you see this behaviour. Once this mindset has been established, there is a sequence of steps we must avoid to be able to effect change. These are as follows: 1. Do not allow your reactions to be based on what your child is saying.
Parenting
Psychology
fromSilicon Canals
1 month ago

What neuroscience reveals about people who need to be alone after socializing - Silicon Canals

Introversion involves lower dopamine reactivity to social stimuli and higher acetylcholine activation during solitude, not a draining social battery that recharges.
Pets
fromwww.mercurynews.com
1 month ago

Looking for a small pet? Consider a domestic rat

Domesticated rats are clean, intelligent, social, affectionate pets that thrive with enrichment and companionship but have short lifespans of two to three years.
fromFast Company
17 years ago

Talking About Nerve!

I received an email recently that claims Wal-Mart senior management has been calling mandatory meetings for the company's employees in which the employees are told they "cannot" vote for the Obama-Biden ticket "or any other employee-friendly, union-friendly candidates for political office". It's not an urban legend, according to the sources I checked. This makes me so angry I just boil. When it comes to the Constitution, I am a rabid supporter.
fromFuturism
2 months ago

Scientists Say Go Ahead, Keep Gooning

Adult content has never been as accessible as it is now, thanks to the internet. Hell, online smut played a major role in the rise of the web itself in the 1990s. With that glut of porn, some have voiced concerns that some people are consuming too much of the stuff or even becoming addicted, which they claim could have consequences like regulating emotions or impaired sexual functioning.
Public health
fromNature
1 month ago

The age of animal experiments is waning. Where will science go next?

Last November, the UK government announced a bold plan to phase out animal testing in some areas of research. Animal tests for skin irritation are scheduled for elimination this year, and some studies on dogs should be slashed by 2030. The long-term vision is 'a world where the use of animals in science is eliminated in all but exceptional circumstances'.
Science
fromSilicon Canals
1 month ago

What neuroscience reveals about people who replay conversations in their head for hours after they happen - Silicon Canals

Neuroscientists have a name for the brain network that fires up when you're not focused on an external task: the default mode network, or DMN. It's the constellation of regions - the medial prefrontal cortex, posterior cingulate cortex, and angular gyrus among them - that hums to life when you daydream, reflect on yourself, or think about other people's mental states.
Psychology
fromNature
1 month ago

Health effects linger 20 generations after rats are exposed to fungicide

Exposure to a fungicide induced changes to gene expression in rats that persisted for at least 20 generations. It also increased the chance of offspring developing kidney disease, obesity or experiencing complications when giving birth, according to the longest-running study of 'epigenetic' changes in mammals.
Science
fromNature
1 month ago

Daily briefing: The new alternatives to animal testing

Mini 3D 'organoids' are slowly phasing out animal testing in some areas of research. These laboratory-grown tissue structures can model human biology more accurately than traditional animal models, reducing the need for animal experimentation while providing more relevant data for drug development and disease research.
Science
Psychology
fromPsychology Today
1 month ago

How the Brain Chooses What Matters

Selective sensory prioritization can improve clarity by letting one modality dominate when multisensory integration would create competition or reduce precision.
#primate-welfare
Science
fromArs Technica
1 month ago

Boozy chimps fail urine test, confirm hotly debated theory

Chimpanzees regularly consume fermented fruit containing significant alcohol levels, supporting the evolutionary theory that human alcohol attraction originated millions of years ago in great apes.
fromNature
2 months ago

Still conscious? Brain marker signals when anaesthesia takes hold

They then used emerging mathematical methods to isolate signals originating from nine brain regions previously implicated in mediating consciousness and examined connections between pairs of these regions. Among them were the parietal cortex, which is at the top of the brain about halfway between the forehead and the back of the skull; the occipital cortex, at the back of the head; and several small, deeper structures, such as one called the thalamus.
Medicine
fromPsychology Today
1 month ago

How Science Is Learning to Explore Ground Truth

Some clinicians have an uncanny quality. A colleague describes herself and others with this instinct as "witchy"-a capacity to know things about patients they haven't said yet, to follow a stray association to a song lyric or a half-remembered cultural reference and arrive, reliably, at something the patient urgently needed to say but couldn't reach on their own. We see with artificial intelligence these intriguing possibilities for discovery, especially as connections that human beings never would see pop out of apparently unrelated data.
Science
Science
fromwww.nature.com
1 month ago

Author Correction: Natural behaviour is learned through dopamine-mediated reinforcement

A .dat-to-.wav conversion error clamped audio values to 1 for 15.9% of data; analyses and figures were updated; results and conclusions remain unchanged.
fromFast Company
1 month ago

How hesitation is a fundamental brain feature, according to neuroscientists

At the Winter Olympics, skiers, bobsledders, speedskaters, and many other athletes all have to master one critical moment: when to start. That split second is paramount during competition because when everyone is strong and skilled, a moment of hesitation can separate gold from silver. A competitor who hesitates too much will be left behind -but moving too early will get them disqualified.
Science
fromPsychology Today
1 month ago

The Hidden Lives of Lab Animals and the Need for Reform

Countless millions of nonhuman animals (animals) of all sorts are used in a diverse array of laboratory research. Their treatment varies from being unspeakably inhumanely abused to being treated with kindness, depending on the questions at hand and the values and attitudes of the researchers themselves. The lives of these animals truly are hidden, and most people are incredulous when they learn that laboratory rats and mice still are not considered "animals" under the current federal Animal Welfare Act.
Science
fromMail Online
2 months ago

Neurologist reveals three simple tricks to help you kick any bad habit

'Have you ever noticed how your day starts?' Khan asks in a YouTube video on his channel, The Brain Project. 'You open your eyes, and your hands already know what to do. Same apps, same path to the kitchen, same routines you never actually chose. 'It feels automatic because, well, it is. Habits aren't a personality trait, they're neural shortcuts your brain builds to save energy.'
Psychology
Science
fromDefector
2 months ago

What A Week Of Freedom Can Do For A Lab Mouse | Defector

Environmental complexity profoundly reduces learned fear and anxiety in laboratory-reared mice after rewilding.
fromPsychology Today
1 month ago

Daily Prophets: How Your Brain Predicts the Future

I am a worrier, and have been for most of my life. At some point, someone dear and smart teased me that I worry about the wrong things. The things that hit me, she noted, were never the things I worried about. For a while that left me feeling like an incompetent worrier-until my research caught up. I realized that the things I worry about often don't end up hurting me precisely because worrying helps me diffuse them ahead of time.
Psychology
Psychology
fromWIRED
2 months ago

A Brain Mechanism Explains Why People Leave Certain Tasks for Later

A ventral striatum–ventral pallidum circuit reduces motivation and causes postponement of actions when those actions are associated with anticipated unpleasant experiences.
Science
fromNature
1 month ago

Daily briefing: Exercise rewires the brain for endurance, in mice

Repeated exercise sessions rewire the brain, making neurons faster to activate and enabling improved running endurance.
Psychology
fromSilicon Canals
1 month ago

Psychology says the compulsion to double-check a locked door isn't anxiety; it's a sign of these 8 rare cognitive traits - Silicon Canals

Compulsive checking often signals heightened cognitive abilities, including exceptional pattern recognition, advanced mental simulation, and hypervigilant anomaly detection.
Science
fromwww.nature.com
1 month ago

De novo design of GPCR exoframe modulators

High-resolution GPCR structures and advanced methods reveal activation, transducer coupling, and allosteric mechanisms that enable targeted drug discovery and new therapeutic strategies.
fromPsychology Today
1 month ago

Tool Use By Animals: Why the Hype and Why It's So Important

Recently, two unexpected examples by a wild wolf and a domesticated cow named Veronika attracted global attention and once again opened the door for experts and others to weigh in on the question, "Are these really examples of tooling?" Many people are eager to know more about the nitty-gritty details of tooling, so I am thrilled that Dr. Benjamin Beck, an expert in this area, could answer a few questions about this fascinating behavior.
Science
Science
fromwww.scientificamerican.com
2 months ago

Why Your Brain Puts Off Doing Unpleasant Tasks

A ventral striatum–ventral pallidum circuit in macaque brains acts as a motivation brake, and suppressing it reduces hesitation for unpleasant tasks.
Science
fromHarvard Gazette
2 months ago

Want to speed brain research? It's all in how you look at it. - Harvard Gazette

SmartEM uses machine learning to guide common single-beam scanning electron microscopes in real time, increasing scanning speed sevenfold and democratizing high-resolution connectomics.
Science
fromPsychology Today
2 months ago

Do Dogs Enjoy Playing More Than Cats, Rats, or Dolphins?

Joy serves as a unifying, evolved positive emotion across species that motivates adaptive behaviors, can become maladaptive in excess, and is difficult to measure.
Science
fromNature
2 months ago

Can't get motivated? This brain circuit might explain why - and it can be turned off

A neural pathway functions as a 'motivation brake' that suppresses task initiation; suppressing it restores goal-directed behavior in macaques.
fromNature
2 months ago

Untangling the connection between dopamine and ADHD

Haavik was surprised to hear this because the scientific data do not suggest an unequivocal link between low levels of the neurotransmitter dopamine and ADHD. But the idea that low dopamine is a direct cause of ADHD is a common misconception, one that's amplified on social media and even in popular books about the condition. The reality, Haavik and other researchers say, is that the causes of ADHD are more diverse and nuanced than a simple deficit in one chemical cue in the brain.
Science
Science
fromNature
2 months ago

Developmental convergence and divergence in human stem cell models of autism - Nature

Distinct rare mutations and common genetic variation jointly shape ASD risk, yet convergent molecular pathology and early fetal neurodevelopmental mechanisms can be studied using stem-cell models.
fromFuturism
2 months ago

Scientists Preparing to Simulate Human Brain on Supercomputer

The team, which is being led by Jülich neurophysics professor Markus Diesmann, will leverage the Joint Undertaking Pioneer for Innovative and Transformative Exascale Research (JUPITER) supercomputer for their simulation. JUPITER is currently the fourth most powerful supercomputer in the world according to the TOP500 list, and features thousands of graphical processing units. The team demonstrated last month that a " spiking neural network " could be scaled up and run on JUPITER, effectively matching the cerebral cortex's 20 billion neurons and 100 trillion connections.
Science
fromNature
2 months ago

Canny cattle: at least one cow knows how to use tools

An Austrian cow has shown that some bovines are intelligent enough to employ objects for their own ends.
Science
Science
fromwww.nature.com
2 months ago

Scalable and multiplexed recorders of gene regulation dynamics across weeks

CytoTape enables multiplexed, genetically encoded, spatiotemporally scalable recording of gene regulation dynamics in single cells for up to three weeks with minute-scale resolution.
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