#neural-imprinting

#neural-imprinting

Galen Buckwalter, a 69-year-old research psychologist and quadriplegic, participated in a brain implant study to contribute to science that aids those with paralysis. The six chips in his brain decode movement intention, allowing him to operate a computer and feel sensations in his fingers again.

Social foraging strategies illustrate the balance between competition and cooperation, where individuals either produce resources or exploit the efforts of others, navigating ecological and social constraints.

To characterize CREs and TFs for neocortical ExNs, we used Arpp21-Gfp or Fezf2-Gfp transgenic mice and enriched GFP-expressing neocortical upper layer (L2-4) intratelencephalic (IT) neurons or deep layer (L5-6) predominantly extratelencephalic (ET) neurons, respectively, from neonatal mice (postnatal day (PD) 0), an age at which neocortical ExN identity and connectivity are established.

This could open up some interesting possibilities for therapeutic interventions for depression-like behaviors or maladaptive changes in motivational behaviors down the road where microglia are known to play a really important role.

The human brain is engineered to ignore most of what it sees and hears, according to the neuroscientists I interviewed for the audio original Viral Voices. If that's the case, how are you supposed to make a memorable impression? The empowering news is that if you understand how the brain works, what it discards, and what it pays attention to, you'll be far more persuasive than you've ever imagined. Persuasive people have influence in their personal and professional lives.

They created an artificial 'mental map', with pleasantness along one axis and bodily reactions along the other, and charted how the brain responded while watching clips from films. The results revealed clear groupings in the way that our brains represent emotion - with guilt, anger and disgust in one corner and happiness, satisfaction and pride in the other.

Neuroscientists have a name for the brain network that fires up when you're not focused on an external task: the default mode network, or DMN. It's the constellation of regions - the medial prefrontal cortex, posterior cingulate cortex, and angular gyrus among them - that hums to life when you daydream, reflect on yourself, or think about other people's mental states.

At the Winter Olympics, skiers, bobsledders, speedskaters, and many other athletes all have to master one critical moment: when to start. That split second is paramount during competition because when everyone is strong and skilled, a moment of hesitation can separate gold from silver. A competitor who hesitates too much will be left behind -but moving too early will get them disqualified.

The team, which is being led by Jülich neurophysics professor Markus Diesmann, will leverage the Joint Undertaking Pioneer for Innovative and Transformative Exascale Research (JUPITER) supercomputer for their simulation. JUPITER is currently the fourth most powerful supercomputer in the world according to the TOP500 list, and features thousands of graphical processing units. The team demonstrated last month that a " spiking neural network " could be scaled up and run on JUPITER, effectively matching the cerebral cortex's 20 billion neurons and 100 trillion connections.

There was a group of neurons that predicted the wrong answer, yet they kept getting stronger as the model learned. So we went back to the original macaque data, and the same signal was there, hiding in plain sight. It wasn't a quirk of the model - the monkeys' brains were doing it too. Even as their performance improved, both the real and simulated brains maintained a reserve of neurons that continued to predict the incorrect answer.

I am a worrier, and have been for most of my life. At some point, someone dear and smart teased me that I worry about the wrong things. The things that hit me, she noted, were never the things I worried about. For a while that left me feeling like an incompetent worrier-until my research caught up. I realized that the things I worry about often don't end up hurting me precisely because worrying helps me diffuse them ahead of time.

It might come as a surprise to learn that the brain responds to training in much the same way as our muscles, even though most of us never think about it that way. Clear thinking, focus, creativity, and good judgment are built through challenge, when the brain is asked to stretch beyond routine rather than run on autopilot. That slight mental discomfort is often the sign that the brain is actually being trained, a lot like that good workout burn in your muscles.